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Scientists unravel link between alchohol and cancer

Think twice about that frothy, bubbly alcohol you consume as scientists have issued a new warning about its health effects by unravelling the linkage between it and cancer.

Alcohol damages the DNA of stem cells responsible for producing new blood, according to a mouse study which may explain the link between drinking and cancer, scientists said on Wednesday.

Health watchdogs have long warned that alcohol consumption contributes to seven types of cancer — of the mouth, throat, larynx or voice box, oesophagus or food pipe, breast, liver and bowel.

What was not well understood was: how?

For the new study, published in the science journal Nature, researchers gave lab mice diluted alcohol, known chemically as ethanol.

They then used chromosome and DNA analysis to examine genetic damage caused by acetaldehyde, a chemical produced when the body processes alcohol.

“They found that acetaldehyde can break and damage DNA within blood stem cells, leading to rearranged chromosomes and permanently altering the DNA sequences within these cells,” Cancer Research UK, which helped fund the research, said in a statement.

“It is important to understand how the DNA blueprint within stem cells is damaged because when healthy stem cells become faulty, they can give rise to cancer.”

DNA damage can lead to cell death, but can also trigger the body’s natural repair mechanisms. However, if the DNA is repaired incorrectly, it can lead to cancer.

“While some damage occurs by chance, our findings suggest that drinking alcohol can increase the risk of this damage,” said lead author Ketan Patel of the MRC Laboratory of Molecular Biology in Cambridge.

The team also examined how the body fights against alcohol damage using a family of enzymes called ALDH, which turn acetaldehyde into acetate, which cells can use as energy.

Millions of people — particularly from Southeast Asia — either lack these enzymes or carry faulty versions, said the team. And mice lacking ALDH, given alcohol, suffered four times as much DNA damage.

“Our study highlights that not being able to process alcohol effectively can lead to an even higher risk of alcohol-related DNA damage and therefore certain cancers,” said Patel.

It may be a contributor to an “extremely high prevalence” of throat cancer in countries such as China, commented Malcolm Alison of the Queen Mary University of London, who was not involved in the study.

Commentators welcomed the paper’s contribution to the knowledge base.

“This is beautiful work, which puts our finger on the molecular basis for the link between alcohol and increased cancer risk and stem cells. Very important,” said Magdalena Zernicka-Goetz of the University of Cambridge.

Diabetes kills only careless people – Obasanjo

Former President Olusegun Obasanjo on Friday morning led hundreds of people on road walk  for diabetes awareness in Abeokuta, the Ogun State capital, saying  “diabetes kills only careless people.”
Obasanjo  who was joined in the road walk by the Oluwo of Iwoland, Oba Abdulrasheed  Adewale Akanbi (Osun State) and Commissioner of Health in Ogun State, Dr. Babatunde Ipaye, added if one took care of oneself, one would discover that “diabetes is not a killer disease.”
The Ebora Owu who noted he is now  well above 80 and could walk  with agility despite being diabetic(covering a distance of 1km  uphill of the distance on foot during the walk), lamented that many of the nation’s youth rarely exercise.
“Diabetes is not a disease that should kill, I was diagnosed to be diabetic more than 30 years ago but rather, I am growing strong, if you don’t believe I am growing strong and you didn’t witness this walk, come and see me at night, you will know I am growing strong, come and see me in the morning, you will know I am growing, even in the afternoon, you will know I am growing strong.
“What is necessary is a management of diabetes. Some people said some diseases are incurable, but diabetes is manageable and compliant.
“My headmaster in primary school was diagnosed at the age of 50 and died at age 85, you will agree with he tried.
“What to do is that if you’re diabetic, don’t be nonchalant about it and don’t eat carelessly. Three things are important, the food you eat, regular exercise and prescribed medication, those are the three most important things.
“You can be diabetic and still lives till 100, I don’t know when I would die but I am above 80 and many of the youth could not catch up with my pace during  the exercise this morning, many of them were running after me.
” This is my message. Whether you’re diabetic or you have a family or friend with diabetic, diabetes is not a killer disease or it should not be a killer disease unless you are careless,” Obasanjo said.
The about two kilometre walk which began at the Marque within the sprawling Olusegun Obasanjo Presidential Library(OOPL), Abeokuta, coursed through MKO Abiola Way and had 15 minutes stop – over at the premises Sunny Yinka Oil on same before turning to end it at the take off point.
The road walk was organized by the Southwest zone of the Diabetes Association of Nigeria(DAN) in collaboration with OOPL to mark the 2017 edition of World Diabetes Day.

I’m tired of staying alone, 87-year-old ex-senator defends wedding

 

An 87-year-old lawyer and former lawmaker, Senator Cyrus Nunieh, said he decided to marry another wife because he was alone and needed a companion.

Nunieh officially married a lady in her 40s on Tuesday at the Presidential Hotel in Port Harcourt, the Rivers State capital.

The former member of the National Assembly, who said he was now a king in Ogoniland, River State, explained that he had been alone after his former wife died in 1991.

Speaking on the wedding Nunieh pointed out that his children were all adults, who had ventured into various business of their own, adding that he could no longer cope with loneliness.

He described his new wife, Rosemary, as an intelligent woman, who would always be there for him and share ideas with him.

“I cannot continue to stay alone. I love her and she loves me. We understand each other and she is also intelligent. In marriage, there are advantages somewhere and disadvantages in other areas.

“There is no limitation in age. Some may say you are old; you may soon die. But some were dead even before they were born. Some were one year or two years old and they die. Death is not always dependent upon a man’s age,” he said.

About her new wife, Nunieh said, “You know that rose is the best of all flowers and we have two Marys in the Bible; we have Mary, the mother of Jesus and Mary Magdalene.

“She too (Rosemary) is a believer of the Bible. But why are you particular about her age? She is not an infant. She is a very charming woman.”

The Punch

‘Sugar daddy’ website targeting Belgian students faces legal fight

 

Belgian ministers have said they will take legal action in an attempt to force a website that links young women and rich men to remove huge adverts near the country’s universities.

Trucks bearing large posters promoting Richmeetbeautiful, which describes itself as a “sugar daddy and sugar baby dating site”, have appeared on the outskirts of campuses in Brussels in recent days. The promotional campaign suggests: “Improve your style of life. Get a sugar daddy”.

After success in Scandinavia, the Norwegian company behind the website says it hopes to recruit 300,000 Belgian registrations by the end of 2018. It claims it is merely offering a “Fifty Shades of Grey” experience, a reference to the erotic novel that chronicles the relationship between a college graduate and a young business magnate.

The site, however, has been accused of encouraging prostitution and playing on the financial insecurity of the young.

A minister for women, Isabelle Simonis, and a minister for education, Jean-Claude Marcourt, in the Francophone administration in Brussels, have declared they intend to launch a criminal proceeding against the firm for inciting debauchery and prostitution, and to force the suspension of its campaign on public order grounds.

Simonis said: “This scandalous and alarming publicity demonstrates that this site encourages the prostitution of young female students. The masks fall in relation to those ‘sugar-dating practices’ that have been causing concern for a while.

“In addition to encouraging young girls to sell their bodies, this phenomenon enhances male dominance and marks a decade-long reversal in the relationship between men and women. It is time to act decisively, through awareness, but also by using all possible legal means.”

The website’s chief executive, Sigurd Vedal, rejected any link to prostitution, suggesting money matters always play a role in romantic relationships.

“Prostitution is not promoted, but the financial aspect is part of any relationship”, he said. “It is a matter of romantic relations between two people who set their own conditions.

“We do not have to police and control how people design their relationships. Women seek powerful, intelligent, brilliant men. This is undoubtedly the most fascinating part, this very strong demand in women. Since Fifty Shades of Grey, they are more liberated and can express these requests.”

Vedal said his company expelled signs of any formal soliciting on the site, though he admitted he was not able to control what happened outside of his web pages.

Similar sites have previously targeted university students in the UK. The US-based SeekingArrangement.com was found in 2015 to be offering premium membership to users with a university email address.

Renaud Maes, a sociologist, told the Belgian newspaper Le Soir that beyond clamping down on advertising campaigns, the authorities needed to look at why the sites were successful.

“What seems to me most important to point out is that student prostitution is based on the growing precariousness of students,” she said. “If we really want to stop this, it is not enough to prevent advertising from reaching students … [we] must be relevant and fight precariousness.”

Man crashes rented Lamborghini, trying to impress lady

A drunken man who tried to impress a woman he met at a bar raced after her in a rented Lamborghini – but then crashed into a tree.

In a bid to win over the woman, the driver chased her in the Lamborghini and tried to impress by overtaking her on the street, she told police.

Traffic camera footage shows the Lamborghini Gallardo, rented for £648 per day, swerving right and then left on a highway.
The driver then veers into the other lane, losing control, before slamming into a tree.

The 22-year-old driver, whose surnamed is Teng, was found guilty of drink-driving and has been detained for further questioning in Jinhua City, China.

To add salt to the wounds, the woman then drove by the crash site and recorded a video mocking the man trying to win her affection.

But then she was also arrested for driving without a licence.

Life expectancy in Nigeria now 63, up from 56

 

Life expectancy in Nigeria has increased to 63 years for men and 66 years for women according to a recent study by researchers at the Institute for Health Metrics and Evaluation (IHME) at the University of Washington.

Despite this increase, the study claims that lives lost to communicable diseases like malaria and HIV are still high.

“Life expectancy in Nigeria is growing, but people in many other sub-Saharan African countries are living longer, healthier lives. Communicable diseases like malaria, diarrhea, lower respiratory diseases, and HIV are still taking the lives of far too many Nigerians,” said Jacob Olusanya, director, Center for Healthy Start Initiative.

“Infants and children are at particular risk from these diseases, and neonatal ailments like sepsis and encephalopathy kill thousands of infants. We have much more work to do.”

The 2017 edition of the annual global burden of diseases study (GBD), which is composed of five peer-reviewed papers, was published The Lancet, a medical journal.

The study’s main findings for Nigeria include:

A Nigerian man born in 2016 can expect to live 63.7 years, an increase in life expectancy of 7 years over the past decade. A woman has a life expectancy of 66.4 years, up 8.1 years from 2006.

A Nigerian male born in 2016 will live approximately 55.5 years in good health; a female only 57.2 years. Nigeria has a higher life expectancy than South Africa, Niger, or Cameroon, but it lags behind Kenya, Rwanda, and Ethiopia.

The top five causes of premature death in Nigeria are malaria, diarrheal diseases, HIV, neonatal encephalopathy, and lower respiratory infection. The ailments that cause illness can be very different. Iron-deficiency anaemia, back pain, and migraines are the top causes of years that people live with disability in Nigeria.

“For every 1,000 live births, 46.6 Nigerian children under the age of 5 die. That far exceeds the global figure of 38.4, and the regional average of countries in western sub-Saharan Africa, which is 40.7.”

In 2016, for the first time in modern history, fewer than five million children under age five died in one year, as compared to 1990 when 11 million died.

Researchers attribute this global health landmark to improvements in increased educational levels of mothers, rising per capita incomes, declining levels of fertility, increased vaccination programs, mass distribution of insecticide-treated bed nets, improved water, and sanitation.

“Death is a powerful motivator, both for individuals and for countries, to address diseases that have been killing us at high rates,” said Christopher Murray, director of the Institute for Health Metrics and Evaluation (IHME).

 

FCT residents react to the rise in cross-dressing among men in Nigeria

Some residents of the Federal Capital Territory (FCT) on Saturday expressed surprise by the rise in the number and societal acceptance of cross-dressed men across the country.

Cross-dressers are people who wear clothing typical of the opposite sex; in this case however, popular among men who dress as women.

The News Agency of Nigeria (NAN), reports that police officials made various arrests of young men who have allegedly defrauded wealthy men in Lagos, Zamfara, Rivers and Abuja by presenting themselves as women.

Some of the residents who spoke to NAN said that it was astonishing how young Nigerians seem to be accepting the idea of cross-dressing.

Joy Nduka, a makeup artist, said that she was surprised by the fact that more Nigerians were aaccepting the idea of cross-dressing.

“I first heard of this concept in Nigeria last year when it was in the news that some men dressed like women to dupe rich men they met at bars and hotels.

“I found it a bit funny at first that some men could be easily deceived in that manner by their fellow men.

“However, I later realised that we all focused on the men who were robbed and not on the men who were comfortable dressing like women to commit the crimes.

“It shows the trend is gradually being accepted among Nigerians,’’ she said.

Victor Itamunoala, a marketer, said “We have always had popular TV personality, Denrele Edun, who remain a controversial figure because of his cross-dressing fashion.

“His fashion concept has always had a hint of feminism in it be it with makeup, hairstyles, high shoes and more.

“Nigerians were against his fashion but these days, many people seem to support him and he has inspired more men to dress that way.

“We have gradually seen a number of Nigerian social media personalities become popular for being cross-dressers and the most popular one today is the man that calls himself the `Snapchat queen’, Bobrisky.

“Bobrisky, originally known as Okuneye Idris, has gradually become a celebrity by acting and dressing as a woman.

“We all watched him transform from a dark skinned man to a light skinned woman who now travels the world and gets paid in pounds and dollars by Nigerian fans who take pictures with him.

“This is insane and appalling, especially as all these famous cross-dressers claim to have connections among politicians.

“The next thing we will see is same sex marriage being legalised in Nigeria, this is how such things start’’ he said.

Another resident, Ndidi John said that the trend was catching on among youths because of the influence of foreign movies.

“You cannot eliminate the role of social media, foreign films and now Nigerian celebrities that engaged in cross dressing on the youths.

“But I personally believe that most of them will grow out of it as the advance in age and become less rebellious,” she said.

To reduce chances of divorce, marry between age 28 and 32 –Study

For years, divorce research led us to believe that marrying later is related to lower odds of divorce. But a study from 2015, which has recently resurfaced, has thrown doubt over that conclusion.

Led by the Institute of Family Studies at the University of Utah, the research revealed that couples who marry in their late twenties or early thirties face the lowest odds of divorce.

After analysing data from the 2006-10 and 2011-13 National Survey of Family Growth, the study, which was led by Nick Wolfinger, suggested that to boost the chances of a lasting marriage, couples should get hitched between the ages of 28 and 32.

Unsurprisingly, researchers found that the divorce risk is higher when you’re younger (with couples who marry in their teens having the highest chance of divorce), before steadily reducing towards your late 20s and early 30s.

Experts have dubbed this 28-32 period the “Goldilocks zone,” but as soon as you’re past the just-right age region, the divorce risk starts to increase again, with the chance of divorce increasing five per cent for every year after 45 that a marriage begins.

Study authors suggest this may be because those who get married at a young age may not have looked around enough for the right partner, while those who wait longer to get married may have “less of the necessary cognitive and emotional resources to maintain their relationships than those who start around the age of 30.”

Yahoo! News

Any man who sleeps with Ooni’s ex-queen may die – Ifa Priest

Popular Ifa traditionalist, playwright, actor and author, Yemi Elebuibon has revealed that any man who sleeps with the Ooni of Ife’s ex-queen without the appropriate cleansing may die prematurely.

He said this while speaking to SUN about the recent crash of the Ooni’s 17-month-old marriage to his former wife, Olori Wuraola.

While noting that Ooni would not be the first Yoruba Oba to be separated from his wife, Elebuibon stressed that marriage breakup is not very common among Yoruba Obas.

He said: “The wife of the Oba will be asked to consult Ifa and Ifa will give directions on how she will make the necessary atonement for her cleansing. In Yoruba tradition, a woman who has been married to a king cannot lay with any other man even if the marriage breaks up. But when the right atonements have been made, there won’t be problem”.

When asked on the kind of problems which an Oba’s ex-wife might encounter if she refuses to undergo the traditional cleansing rites, Elebuibon said: “For the woman, she might not really have a problem but for any man who sleeps with a queen or marries an ex-queen without the appropriate cleansing, the man may die prematurely, he may be struck with sickness or there might be retrogression in his life”.

He warned that if an ex-queen wants to remarry, she will have to do the cleansing with her new husband. Both of them have to take part in the atonement procedures so that they won’t have any future problem.

“Any marriage she would be going into must not be elaborate. They should go far away and avoid any flamboyant wedding”

 

Saudi Arabia bans 400,000 illegal pilgrims from entering Mecca

Saudi Arabia has banned more than 400,000 illegal pilgrims from entering Mecca for not having Hajj permits, Saudi Press Agency reported on Tuesday.

 

This was highlighted by the interior ministry during a news conference on Hajj security plans that were designed to accommodate more than two million pilgrims expected to perform Hajj 2017.

 

Saudi Arabia has taken serious steps, including fine and jail terms against violators to ensure smooth Hajj operation for the pilgrims.

 

The ministry also announced that until on Tuesday 1.7 million foreign pilgrims and around 200,000 domestic pilgrims had arrived in Mecca.

 

More than 100,000 members of the Saudi security forces will participate in this year Hajj 2017 this week.

 

Saudi Interior Ministry spokesman, Mansour Turki, said that the security services had dismantled a number of militant cells in Mecca and Medina over the past few years.

 

Maj.-Gen. Mansour Al-Turki, a security spokesman from the Saudi Arabian Ministry of Interior, said that strict measures were in place at the entrances to Mecca, Medina and other holy sites as well as airports and seaports.

 

“So, we do not overlook the reality of such potential threats and we take all necessary preventative measures.’’

 

Saudi security guards monitor screens at the national centre for security operations in the holy city of Mecca, Saudi Arabia August 29, 2017.

 

Turki said the security forces had taken all necessary measures to prevent a stampede like the one that killed hundreds of pilgrims in 2015, without providing details.

 

But he also urged pilgrims to abide by their assigned schedule for performing the sacred rituals.

 

“Each group must abide by the specified paths assigned to each while throwing the jamarat,” he said, referring to one of the critical stages of Hajj, when pilgrims conduct the ritual stoning.

NAN